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ARTHRITIS

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Glucosamine for Joint Pain? (Osteoarthritis) 

A round-up of scientific research on glucosamine:

Comparing glucosamine to ibuprofen 'for osteoarthritis,] these scientists concluded, "In contrast to NSAID 'in this case ibuprofen, though it may be true of aspirin and other 'aspirin type drugs,'] no serious or fatal side effects have been reported for glucosamine. Our critical evaluation indicates that glucosamine is safe under current conditions of use and does not affect glucose metabolism 'diabetes.]"

From: Food Chem. Toxicology, vol. 43, 2005. By: Drs. Anderson, Nicolosi & Borzelleca, Dept of Internal Med., U. of Kentucky, 1030 S. Broadway, Lexington, KY 40504-2681. USA. Emphases added.

"To determine the effectiveness of oral glucosamine...'and] ibuprofen for the relief of joint pain in osteoarthritis...

"In practice glucosamine can be used as an alternative to anti-inflammatory drugs 'such as ibuprofen] and analgesics 'Tylenol (t.m)] or as a useful adjunct to standard analgesic 'pain-relieving] therapy." Emphases added.

From: Brit. J. Community Nursing, vol. 7, 2002. By Ruane & Griffiths, Kings College, London, UK.

"...These data suggest that a ...mechanism is operative in glucosamine-induced insulin resistance and glucosamine impairs glucose transport stimulated by various stimuli..."

From: Biochem. Biophys. Res. vol. 292, 2002. By: Drs. Heart & Sung, Dept. of Physiology & Biophys., U. of So. Cal., Los Angeles, CA 90089-9142, USA. Emphases added.

NOTE: This would indicate some caution to diabetics in using glucosamine.

"Glucosamine...naturally occurring in the connective and cartilage tissues, contributes to maintaining the strength, flexibility, and elasticity of these tissues..."

From: J. Leucocyte Biol., vol. 4, 2002. By: Drs. Hua, Sakamoto and Nagaoka, Dept. of Biochemistry, Juntendo U., School of Med., Tokyo, Japan.

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