"...'Ashwagandha] has been used to stabilize mood in patients with behavioral disturbances. The present study investigated the the...antidepressant actions of 'an ingredient] from 'Ashwagandha] roots, in 'animals.] WSG 'the ingredient] (20 and 50mg. per kilogram) 'a kilogram is 2.2 lbs.] was administered orally once daily for 5 days and the results were compared by those elicited by the 'drug] benzodiazepine lorazepan (0.5mg/kg injected) for 'drug-reducing anxiety] and by the tricyclic anti-depressant, imipramine...for the antidepressant investigations...

"WSG 'Ashwagandha component] induced an 'anti-anxiety effect,] comparable to that produced by lorazepam..."

"Further, both WSG 'Ashwagandha component] also exhibited an antidepressant effect, comparable with the induced by imipramine 'drug]...

"The investigations support the use of WS 'Ashwagandha component] as a mood stabilizer in clinical conditions of anxiety and depression..."

In: Phytomedicine, vol. 7, 2000. By: Drs. Bhattacharya, Sairam & Ghosal, Dept. of Pharmacology, Inst. of Med. Sciences, Banaras H. U., Varanasi, India.