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Breast Cancer--Grapes
Beat Out Drug
"Previous reports have shown elevated prostaglandin in women with
metastic breast cancer... We have shown that 'cyclooxygenase COX 1 &
2--the substances that are inhibited by aspirin] are amplified in
human breast tumors...and that inhibition of both COX 'types] blocked
development & induced regression of 'animal] mammary tumors, induced
'cell death in tumors] and inhibited 'growth of new blood supplies to
the tumor.]
"...we compared 'substances that inhibit one COX type with substances
that inhibit both types.] Resveratrol 'in red and black grapes],
which inhibits both 'types] was the most effective anti-proliferative
agent examined." ...Cottril, Prosperi, Mihm, & Bauer, College of
Med. & Comprehensive Cancer Ctr., Ohio State U., Columbus, and Div. of
Pharmacology, Ohio State U.
From the Annual
Meeting of FASEB, 2002. FASEB is an umbrella organization comprising
American Physiological Soc., Amer. Soc. for Biochemistry & Molecular
Biology, Amer. Soc. Investigative Pathology, Amer. Assn. of
Immunologists, Amer. Assn. Anatomists, Amer. Soc. Nutritional Sciences,
etc.
All emphasis added.
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