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CANCER

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Breast Cancer--Grapes Beat Out Drug
"Previous reports have shown elevated prostaglandin in women with metastic breast cancer... We have shown that 'cyclooxygenase COX 1 & 2--the substances that are inhibited by aspirin] are amplified in human breast tumors...and that inhibition of both COX 'types] blocked development & induced regression of 'animal] mammary tumors, induced 'cell death in tumors] and inhibited 'growth of new blood supplies to the tumor.]

"...we compared 'substances that inhibit one COX type with substances that inhibit both types.] Resveratrol 'in red and black grapes], which inhibits both 'types] was the most effective anti-proliferative agent examined." ...Cottril, Prosperi, Mihm, & Bauer, College of Med. & Comprehensive Cancer Ctr., Ohio State U., Columbus, and Div. of Pharmacology, Ohio State U.

From the Annual Meeting of FASEB, 2002. FASEB is an umbrella organization comprising American Physiological Soc., Amer. Soc. for Biochemistry & Molecular Biology, Amer. Soc. Investigative Pathology, Amer. Assn. of Immunologists, Amer. Assn. Anatomists, Amer. Soc. Nutritional Sciences, etc.

All emphasis added.

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