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CANCER

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New Drug May Extend Breast Cancer Treatment after Tamoxifen

Pomegrantes to the Rescue?

Isn't it wonderful? Women who have had the required 5-year regimen of Tamoxifen will be able to take a new drug to extend their protection. One question is--how does the new drug work and another is--what are the side effects? Newspaper reports say that the drug is an "aromatase inhibitor."

Fine. Now read this--Aromatase is the enzyme that aids in the body's synthesis of estrogen. So, estrogen being potentially carcinogenic, reducing women's estrogen production should be helpful.

"The ability to effect a blockage of endogenous 'within the body] active estrogen ...synthesis was shown by polyphenols from fermented and 'unfermented] pomegranate juice...and oil, which inhibited aromatase activity by 60-80%..." Emphasis added.

By Kim, Mehta, Yu, Neeman, Rabi, Poirier, Kaplan, Lansky, et al., Dept. of Pharmacy, Pusan Nat. U., Korea. In Breast Cancer Res. Treat. vol. 27, 2002.

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