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These are not new studies, but our attention was called to them when we
noted the presence of kola nut extract in some diet pills.
"Kola-nut extract induced a number of overt 'nerve toxicity] signs in
'animals.} A decrease in the total body weight and an increase in
the absolute weights of the liver, kidney, brain and testis were
observed after 18 weeks oral administration." ...J. Applied Toxicology.
Emphases were added.
"These data suggest that the possible role of kola nut chewing in human
cancer 'disease] should be explored in countries where kola nuts are
widely consumed as stimulants."...Food Chemical Toxicology.
"The influence of fresh kola-nut extract on locomotor 'motion] activity
of 'animals] was studied using direct...observations...It was observed
that a medium dose (5mg. per kilogram) significantly increased the
locomotor activities whereas a low dose (2.5mg. per Kilogram) had no
effect and a high dose (10mg. per Kg.) showed depressive
'emphasis added] effects on the 'motion] activities."...Acta Physiol.
Pharamocol. Bulg.
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